John Astle, MD, PhD

Assistant Professor of Pathology



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John Astle, MD, PhD

Assistant Professor of Pathology


Phone: (414) 805-8844

FAX:      (414) 805-8735

Office Address

Department of Pathology Medical College of Wisconsin

9200 West Wisconsin Avenue

Milwaukee, WI, USA 53226

Dr. Astle is responsible for evaluation and diagnosis of hematopathology specimens at the Medical College of Wisconsin/Froedtert Hospital and Children’s Hospital of Wisconsin, teaching medical students and pathology trainees, and helping to advance the field of pathology.

  • Research Interests
  • Professional Background
  • Educational Background
  • Board Certifications

Astle JM, Rose MG, Racke FK, Tormey CA, Siddon AJ.

R634W KIT Mutation in an Adult With Systemic Mastocytosis.

Lab Med 2017 May 18;


Astle JM, Simpson LS, Huang Y, Reddy MM, Wilson R, Connell S, Wilson J, Kodadek T.

Seamless bead to microarray screening: rapid identification of the highest affinity protein ligands from large combinatorial libraries.

Chem Biol 2010 Jan 29;17(1):38-45


Kathiriya IS, King IN, Murakami M, Nakagawa M, Astle JM, Gardner KA, Gerard RD, Olson EN, Srivastava D, Nakagawa O.

Hairy-related transcription factors inhibit GATA-dependent cardiac gene expression through a signal-responsive mechanism.

J Biol Chem 2004 Dec 24;279(52):54937-43