NPM1 Mutation Analysis 
Mnemonic MISC
CPT 81310
Test Code 3509949
Synonyms CN-AML prognostication, NPM1 exon 12
Test Includes  
Specimen Whole Blood or Bone Marrow
Volume 5.0 mL (3 mL Bone Marrow)
Container Lavender Top (EDTA) Tube
Special Instructions Due to stability testing can only be collected Monday-Friday AM, sample has only a 48hr stability.
Specimen Prep Do NOT centrifuge
Storage Refrigerated
Transport Temp Refrigerated
Stability Rm Temp 1 hour
Stability Refrig 48 hours
Stability Frozen Unacceptable
Methodology Quantitative Reverse-Transcription Polymerase Chain Reaction
Rejection Criteria Serum, plasma, or FFPE tissue. Specimens collected in anticoagulants other than EDTA. Severely hemolyzed or clotted specimens.  
Reference Value   
Performed/TAT Three times per week   5-7 days